A young Aji Mathew is a communist who goes the whole nine yards for the ideologies he believes in. When the girl he loves leaves to the US out of the blue and her parents fix her wedding, Aji is left with just a fortnight to reach the country albeit with no passport or visa. How far he is willing to go for love forms the plot.
Jayaraman (Mohanlal) is born as a blind man but with heightened senses of smell, sound and touch. He is trained in the martial art of Kalaripayattu. He works as an elevator operator in an apartment where many reputed people live. One day he happens to encounter a murder in a flat. The killer escapes and Jayaraman is charged with the murder. To prove his innocence to the law, Jayaraman must now find and kill the true murderer.
Krishnan, who has been living away from his family and friends in Mumbai, gets a call from his friend Ganga in Kerala, out of the blue. He senses danger, and leaves for Kammattipadam, where both of them grew up.
Dr. Rohini Pranab , a doctor who runs an NGO and a shelter home for destitute girls, is targeted by human-traffickers. Her shelter home is attacked and all the children are taken. Naveen finds her sister kidnapped right in front of his eyes by the same gang.
Mathew is a graduate in software engineering, but is now jobless. He is waiting for his good time to get a good job. Mathew has borrowed some money as loan. Now he cannot give it back as he has no job. Mathew's childhood friend Jeena Johnykkutty is ready to help him as she could. She has a job. Her father Johnykkutty does not like Mathew and he always tries to trouble Mathew whenever he gets a chance. At this time Mathew's good time arrives; but along with it many problems too. The gripping events that follow plot the rest of 'Neram'.
Georgekutty lives a happy life with his wife and daughters. Things take a turn when his daughter gets indecently filmed using a hidden camera, by the son of a police inspector.